As you may have already experienced, many conferences are being canceled or going virtual due to COVID-19. With strict safety measures, APLX2021 will convene as an in-person conference, like many other conferences that took place in Taiwan in 2020. With the downward trend of COVID cases worldwide, Taiwan is expecting to gradually loosen its restrictions on international travel. However, we still foresee safety requirements such a COVID-19 RT-PCR test report, a vaccination proof, or a shortened quarantine for international presenters. At the same time, we are also working on possible virtual presentations for our international attendees, should travel restrictions forbid them from coming to Taiwan. The organizing committee will continue to monitor the situation and post updates on our website.